Proton Pump Inhibitors | The American Association For Justice

Proton Pump Inhibitors


Proton-Pump Inhibitors (PPls), such Nexium, Pri1osec, and now their generic and OTC versions, are some of the most widely prescribed, over-prescribed, and profitable medications ever marketed. For more than 25 years, they were marketed to doctors as completely safe, and they are incredibly effective at preventing simple heartburn, an unapproved indication. As a result, the majority of PPI prescriptions have been for unapproved indications and approved for OTC use.

Despite selling these drugs with no warnings for over two decades, PPls are not risk-free. There are numerous injuries associated with PPI use, including bone fractures, infections, magnesium deficiency, dementia, cancer, and Acute Interstitial Nephritis (AIN), Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD), leading to End Stage Renal Disease (ESRD). Starting in 2010, a bone fracture warning was added. In 2011, a magnesium deficiency warning was added. In 2014, an AIN warning was added. Finally, in 2016 multiple studies concluded that PPI’s dramatically increase a person’s risk of kidney failure and kidney disease. However, there is still no warning for CKD and there has never been any warning on OTC PPI products.

The litigation involves product liability claims against the manufacturers of PPls, which include Nexium, Prilosec, Prevacid, Protonix, AcipHex, Zegerid, Dexilant, Vimovo and their generic and over-the-counter (OTC) counterparts.


Benefits & Resources:

The Proton-Pump Inhibitors (PPI) Litigation Group helps members investigating and litigation claims against the manufacturers of PPls. Members of the group have access to a secure, members-only list server and document library, as well as meeting and education programs throughout the year.

Derek T. Braslow
Pogust Braslow &
Millrood LLC
Eight Tower Bridge
161 Washington St., Suite 940
Conshohocken, PA 19428
Phone: 610/941-4204
Fax: 610/941-4245
Tracy Finken Magnotta
Anapol Weiss
One Logan Square
130 North 18th St.
Suite 1600
Philadelphia, PA 19103
Phone: 215/735-0773
Fax: 215/875-7731
Neil D. Overholtz
Aylstock, Witkin, Kreis & Overholtz, PLLC
17 E. Main St., Suite 200
Pensacola, FL 32502
Phone: 850/202-1010
Fax: 850/916-7449
Paul J. Pennock
Weitz & Luxenberg, PC
700 Broadway
New York, NY 10003
Phone: 212/558-5500
Fax: 212/344-0994
$300 annually